TINU syndrome and lymphoid interstitial alveolitis: a new observation

TINU syndrome is a rare entity known Dobrin disease, combining uveitis mostly bilateral and recurrent with acute tubulo interstitial nephritis [AIN] occurring in young adults. The etiology and pathogenesis of this syndrome remain unknown. Aim: To report a new case of TINU syndrome and to discuss its etiopathogenesis. This 33 year old women is hospitalized for exploration of acute renal failure, in a context of deterioration of general condition, associated with a unilateral anterior uveitis. The bronchoalveolar lavage showed lymphoid interstitial alveolitis with CD4 and the renal biopsy found lesions characteristic of AIN. Evolution under cortico'id treatment was favorable. Lymphoid interstitial alveolitis associated with TINU syndrome has been reported only twice before. The discovery of a TINU syndrome must practice bronchoalveolar lavage in search of sub clinical pulmonary involvement

[Fatal post transfusional hepatitis CMV of fatal outcome]

The cytomegalovirus [CMV] infection is most often asymptomatic, serious forms are confined to immunocompromised. We report a new case of post-transfusionnel hepatitis CMV of fatal outcome. A 83 year old man, asthmatic known for 26 years treated of corticosteroids, without particular hepatic antecedents, has presented an acute hepatitis post-.transfusionnel CMV of fatal outcome. The authors suggest widening the indications transfusion with the blood without leucocytes to the old persons fragile and/or whose immunizing status is precarious